[Clinical studies in sultamicillin fine granule in the field of pediatrics]

Jpn J Antibiot. 1988 Dec;41(12):1863-73.
[Article in Japanese]

Abstract

Clinical studies were carried out on sultamicillin (SBTPC) fine granule in the field of pediatrics. The results obtained are summarized below. 1. Thirty children with bacterial infections were treated with SBTPC fine granule. The clinical results were excellent in 24 and good in 5, with an efficacy rate of 96.7%. 2. Bacteriological screening identified 26 pathogenic organisms of which 14 were Gram-positive cocci and 12 Gram-negative rods. Eradication rates were 91.7% in Gram-positive cocci and 66.7% in Gram-negative rods. 3. As side effects, diarrhea was observed in 12.9%, loose stool in 16.1% and eosinophilia in 3.2% of the patients. From the above results, it appeared that SBTPC fine granule was a useful drug for treating bacterial infections in the field of pediatrics.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Age Factors
  • Ampicillin / pharmacology
  • Ampicillin / therapeutic use*
  • Ampicillin Resistance
  • Bacteria / drug effects*
  • Bacteria / isolation & purification
  • Bacterial Infections / drug therapy*
  • Bacterial Infections / microbiology
  • Child
  • Child, Preschool
  • Dosage Forms
  • Drug Evaluation
  • Drug Therapy, Combination / pharmacology
  • Drug Therapy, Combination / therapeutic use
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Sulbactam / pharmacology
  • Sulbactam / therapeutic use*

Substances

  • Dosage Forms
  • sultamicillin
  • Ampicillin
  • Sulbactam