São Paulo State Liver Transplantation Supply Chain Study

Transplant Proc. 2020 Jun;52(5):1247-1250. doi: 10.1016/j.transproceed.2020.02.181. Epub 2020 Jun 2.

Abstract

Background: The number of liver transplantations is increasing worldwide, and Brazil ranks in the second position. It has one of the biggest public health care systems, which is responsible for the coordination and financial funding of transplantation procedures. Meeting the demands of such a large system of transplantation has become a challenge, particularly when attempting to minimize costs of scarce and expensive resources. The aim of this study was to investigate the process of donation, the retrieval of organs, and the transplantation itself using engineering methods based on logistics analyses.

Methods: Three steps were used: study planning, data gathering, and data analysis. Researchers surveyed professionals to acquire raw information based on their observations, experience, and knowledge. Then, a data analysis was conducted, putting together all the information gathered during the previous steps. Bias was removed, and conflicting perceptions were resolved in order to have a standard view on the transplantation process.

Results: Data was gathered between 2014 and 2018 and included 5502 liver donors and 2678 (48.7%) patients who received liver transplants organs. A total of 2824 organs were refused because of logistics issues (transport and handling). Interviews of health care professionals enabled the design of a process map in which 4 stakeholders were identified: patient, physician, organ, and information.

Conclusions: The liver transplantation process is analyzed based on a supply chain methodology applying this knowledge and putting together medical and engineering sciences to promote better efficiency and outcomes for the transplantation program. Future studies should focus on the implementation of these ideas aiming to promote optimization gains in any step of the process.

MeSH terms

  • Brazil
  • End Stage Liver Disease / surgery*
  • Humans
  • Liver Transplantation / economics*
  • Models, Organizational
  • Outcome and Process Assessment, Health Care
  • Postoperative Period
  • Tissue and Organ Procurement / economics
  • Tissue and Organ Procurement / organization & administration*
  • Transplants / supply & distribution*
  • Waiting Lists