Hashimoto's encephalopathy in association with retinitis pigmentosa - First reported case

Ritwik Ghosh; Subhankar Chatterjee; Devlina Roy; Souvik Dubey; Biman Kanti Ray

doi:10.4103/jfmpc.jfmpc_1197_19

Hashimoto's encephalopathy in association with retinitis pigmentosa - First reported case

J Family Med Prim Care. 2020 Mar 26;9(3):1765-1767. doi: 10.4103/jfmpc.jfmpc_1197_19. eCollection 2020 Mar.

Authors

Ritwik Ghosh¹, Subhankar Chatterjee², Devlina Roy¹, Souvik Dubey³, Biman Kanti Ray³

Affiliations

¹ Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
² Department of General Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
³ Department of Neuromedicine, Bangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research and SSKM Hospital, Kolkata, West Bengal, India.

Abstract

Hashimoto's Encephalopathy (HE), also known as steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT), is a proteiform disorder known for its wide spectrum of presentations from subtle neuropsychiatric manifestations, movement disorders, seizures, stroke-like episodes to coma. Here, we report a case of HE which initially masqueraded as bipolar affective disorder (BPAD) and ultimately progressed to generalized tonic clonic seizures and coma. Although SREAT is characterized by exquisite responsive to steroid, in our case it was unresponsive to pulse methylprednisolone therapy. Rapid recovery was noted with intravenous immunoglobulin (IVIG) therapy. This case was also peculiar for its association with non-sydnromic retinitis pigmetosa (RP). To the best of our knowledge, this was the first reported case of HE which was associated with RP.

Keywords: Hashimoto's Encephalopathy; intravenous immunoglobulin; retinitis pigmentosa; thyroid.

Publication types

Case Reports