Coronavirus disease 2019 in pregnancy: early lessons

Am J Obstet Gynecol MFM. 2020 May;2(2):100111. doi: 10.1016/j.ajogmf.2020.100111. Epub 2020 Mar 27.

Abstract

The worldwide incidence of coronavirus disease 2019 (COVID-19) infection is rapidly increasing, but there exists limited information on coronavirus disease 2019 in pregnancy. Here, we present our experience with 7 confirmed cases of coronavirus disease 2019 in pregnancy presenting to a single large New York City tertiary care hospital. Of the 7 patients, 5 presented with symptoms of coronavirus disease 2019, including cough, myalgias, fevers, chest pain, and headache. Of the 7 patients, 4 were admitted to the hospital, including 2 who required supportive care with intravenous hydration. Of note, the other 2 admitted patients who were asymptomatic on admission to the hospital, presenting instead for obstetrically indicated labor inductions, became symptomatic after delivery, each requiring intensive care unit admission.

Keywords: COVID-19; novel coronavirus; pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / etiology
  • Acute Kidney Injury / physiopathology
  • Adult
  • Anesthesia, General
  • Anti-Bacterial Agents / therapeutic use
  • Antihypertensive Agents / therapeutic use
  • Azithromycin / therapeutic use
  • Bronchial Spasm / therapy
  • COVID-19 / complications
  • COVID-19 / diagnosis
  • COVID-19 / physiopathology
  • COVID-19 / therapy*
  • Carrier State*
  • Ceftriaxone / therapeutic use
  • Cesarean Section
  • Diabetes Mellitus, Type 2 / complications
  • Enzyme Inhibitors / therapeutic use
  • Female
  • Fever / physiopathology
  • Health Personnel
  • Hospitalization
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Hypertension / complications
  • Hypertension / drug therapy
  • Intensive Care Units
  • Intubation, Intratracheal
  • Labor, Induced
  • New York City
  • Nicardipine / therapeutic use
  • Occupational Exposure
  • Oxygen Inhalation Therapy
  • Postpartum Hemorrhage / therapy
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / drug therapy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / physiopathology
  • Pregnancy Complications, Infectious / therapy*
  • Pregnancy in Diabetics
  • Respiration, Artificial
  • SARS-CoV-2
  • Uterine Inertia / therapy

Substances

  • Anti-Bacterial Agents
  • Antihypertensive Agents
  • Enzyme Inhibitors
  • Hydroxychloroquine
  • Ceftriaxone
  • Azithromycin
  • Nicardipine