68Ga-DOTATATE PET/MRI for Neuroendocrine Tumors: A Pictorial Review

Clin Nucl Med. 2020 Sep;45(9):e406-e410. doi: 10.1097/RLU.0000000000003085.

Abstract

Neuroendocrine tumors (NETs) constitute a variety of neoplastic entities and exhibit variable degrees of neuroendocrine differentiation and phenotypes, as well as genetic profiles. Ga-DOTATATE PET is a novel imaging technique for NET. Although PET/CT is commonly utilized for oncologic imaging, PET/MRI is particularly suited for NETs, as MRI provides greater soft tissue contrast than CT, allowing for improved detection and characterization of NETs, particularly when liver metastasis is suspected or needs to be ruled out. The current pictorial review aims to illustrate the complementary advantages, as well as pitfalls of Ga-DOTATATE PET/MRI in the evaluation of NETs.

Publication types

  • Review

MeSH terms

  • Humans
  • Magnetic Resonance Imaging / methods*
  • Multimodal Imaging / methods*
  • Neuroendocrine Tumors / diagnostic imaging*
  • Neuroendocrine Tumors / pathology
  • Organometallic Compounds*
  • Positron-Emission Tomography / methods*

Substances

  • Organometallic Compounds
  • gallium Ga 68 dotatate