The use of extracorporeal membrane oxygenation postcardiotomy-A systematic review

J Card Surg. 2020 Aug;35(8):1941-1953. doi: 10.1111/jocs.14694. Epub 2020 Jun 29.

Abstract

Objectives: The use of extracorporeal membrane oxygenation (ECMO) in cardiac surgery has been established in cases of postcardiotomy cardiogenic shock, which is refractory to conventional therapy with inotropes and intra-aortic balloon pulsation support. We sought to examine the literature in a systematic review manner on the outcomes of using ECMO postcardiac surgery.

Methods: A comprehensive electronic literature search was done to identify all the articles that have discussed the use of ECMO postcardiac surgery. The keywords and medical subject headings terms were used to identify the relevant articles. Studies have been screened according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Results: The identified studies have been summarized in each relevant section of this study. Cardiogenic shock postcardiac surgery can benefit from ECMO to varying degrees and the survival for this; otherwise, fatal condition has been shown to be improving through the use of ECMO. However, the decision and timing to initiate ECMO therapy remains selective and is dependent on a range of factors such as patient factor, clinician's judgment, meaning there is no consistent and solid ground regarding the timing of ECMO initiation.

Conclusion: Current evidence suggests that the circulatory support provided by ECMO improves survival rates for postcardiac surgery cardiogenic shock patients who are refractory to inotropic management, without such ECMO support patient mortality rates would be much greater.

Keywords: ECMO; cardiac surgery; cardiotomy; survival.

Publication types

  • Meta-Analysis
  • Systematic Review

MeSH terms

  • Cardiac Surgical Procedures / adverse effects*
  • Extracorporeal Membrane Oxygenation / methods*
  • Humans
  • Postoperative Complications / etiology*
  • Postoperative Complications / mortality
  • Postoperative Complications / therapy*
  • Shock, Cardiogenic / etiology*
  • Shock, Cardiogenic / mortality
  • Shock, Cardiogenic / therapy*
  • Survival Rate
  • Treatment Outcome