Variation in insurance-mortality relationship amid macroeconomic shifts: a study of SEER female-specific cancer patients in USA

Public Health. 2020 Aug:185:130-138. doi: 10.1016/j.puhe.2020.03.006. Epub 2020 Jul 1.

Abstract

Objectives: Health insurance availability and affordability are vital elements in diagnosis and treatment of patients with cancer and thus constitute clinical significance as well. Although past studies have explored the disparity in mortality figures for patients with different insurance statuses, this population-based study is pioneering in analyzing the changes in cancer mortality risks over time amid macroeconomic shifts.

Study design: The study uses Surveillance Epidemiology and End Results (SEER) data of 424,889 non-elderly patients with breast, cervical, ovarian, and uterine cancer diagnosed during 2007-2010 and 2011-2015.

Methods: In addition to discussing incidence figures and insurance patterns, the study uses Kaplan-Meier and Cox's proportional hazard models to examine the changes in survival probability and mortality risks for insurance-stratified patients with female-specific cancer across the two time periods.

Results: Patients without insurance have an increased risk of mortality over time relative to insured patients. Moreover, uninsured patients face this heightened risk more than Medicaid patients.

Discussion: Despite public policy measures as well as advancements in diagnostic facilities and treatment technology, the increased relative mortality of patients without insurance limits the long-term affordability of cancer treatment for economically vulnerable patients in comparison with insured patients.

Keywords: Cancer mortality; Insurance; Macroeconomic conditions; SEER; Treatment affordability.

MeSH terms

  • Adolescent
  • Adult
  • Breast Neoplasms / mortality
  • Female
  • Humans
  • Incidence
  • Insurance Coverage / economics
  • Insurance Coverage / statistics & numerical data*
  • Insurance, Health / economics
  • Insurance, Health / statistics & numerical data*
  • Medicaid / economics
  • Medically Uninsured
  • Middle Aged
  • Neoplasms / economics
  • Neoplasms / epidemiology
  • Neoplasms / mortality*
  • Ovarian Neoplasms / mortality
  • Risk Factors
  • SEER Program
  • United States
  • Uterine Cervical Neoplasms / mortality
  • Uterine Neoplasms / mortality
  • Young Adult