Wearable technologies to measure clinical outcomes in multiple sclerosis: A scoping review

Mult Scler. 2021 Oct;27(11):1643-1656. doi: 10.1177/1352458520946005. Epub 2020 Aug 4.

Abstract

Wearable technology refers to any sensor worn on the person, making continuous and remote monitoring available to many people with chronic disease, including multiple sclerosis (MS). Daily monitoring seems an ideal solution either as an outcome measure or as an adjunct to support rater-based monitoring in both clinical and research settings. There has been an increase in solutions that are available, yet there is little consensus on the most appropriate solution to use in either MS research or clinical practice. We completed a scoping review (using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) guidelines) to summarise the wearable solutions available in MS, to identify those approaches that could potentially be utilised in clinical trials, by evaluating the following: scalability, cost, patient adaptability and accuracy. We identified 35 unique products that measure gait, cognition, upper limb function, activity, mood and fatigue, with most of these solutions being phone applications.

Keywords: Multiple sclerosis; biosensors; mHealth; mobile applications; remote sensing technology; wearable technology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review
  • Systematic Review

MeSH terms

  • Gait
  • Humans
  • Multiple Sclerosis* / diagnosis
  • Multiple Sclerosis* / therapy
  • Outcome Assessment, Health Care
  • Wearable Electronic Devices*