The efficacy and complications of computed tomography guided microwave ablation in lung cancer

Ann Palliat Med. 2020 Sep;9(5):2760-2765. doi: 10.21037/apm-20-255. Epub 2020 Jul 30.

Abstract

Background: This study aimed to explore the effect and safety of computed tomography (CT) guided microwave ablation for lung cancer.

Methods: We retrospectively enrolled CT guided microwave ablation of lung cancer patients in Shanghai Pulmonary Hospital from March 2016 to September 2019. All patients were pathologically confirmed by fine needle biopsy before microwave ablation. We reviewed CT imaging of 45 patients with lung cancer before and after microwave ablation and recorded the complications. Date were analyzed by paired-samples T-test and one-way analysis of variance.

Results: In 45 lung cancer patients received CT guided microwave ablation, the tumor diameter changed from 2.35±0.22 cm before surgery to 2.26±0.19 cm after surgery, average reduction by 0.09 cm (P=0.518). With microwave ablation treatment, the disease control rate reached 82.93%, and the incidence of pneumothorax was 13.3%, with no other related adverse. The successful rate of operation was 100%, and there was no severe or death related adverse.

Conclusions: CT-guided microwave ablation is an effective method in the treatment of lung cancer, with a low incidence of complications. It is a safe and effective method for the treatment of lung cancer.

Keywords: Microwave ablation; effect; lung cancer; safety.

MeSH terms

  • Catheter Ablation* / adverse effects
  • China
  • Humans
  • Lung Neoplasms* / diagnostic imaging
  • Lung Neoplasms* / surgery
  • Microwaves / therapeutic use
  • Retrospective Studies
  • Tomography, X-Ray Computed
  • Treatment Outcome