A rare association of Takotsubo cardiomyopathy with neuroleptic malignant syndrome

Waqas Ullah; Muhammad Arslan Cheema; Ammar Ashfaq; Maryam Mukhtar; Zain Ali; Mamoon Ur Rashid; Vincent Figueredo

doi:10.1080/20009666.2020.1742522

A rare association of Takotsubo cardiomyopathy with neuroleptic malignant syndrome

J Community Hosp Intern Med Perspect. 2020 May 21;10(2):133-137. doi: 10.1080/20009666.2020.1742522.

Authors

Waqas Ullah¹, Muhammad Arslan Cheema², Ammar Ashfaq¹, Maryam Mukhtar³, Zain Ali¹, Mamoon Ur Rashid⁴, Vincent Figueredo⁵

Affiliations

¹ Internal Medicine, Abington, Jefferson Health, Abington, PA, USA.
² Department of Internal Medicine, Abington, Jefferson Health, Abington, PA, USA.
³ Rawal Pindi Institute of Cardiology, Rawalpindi, Pakistan.
⁴ AdventHealth, Orlando, FL, USA.
⁵ Saint Mary Medical Center, Philadelphia, PA, USA.

Abstract

Neuroleptic malignant syndrome is a potentially fatal neurological condition secondary to antipsychotic medication. It is characterized by distinctive clinical findings and autonomic disturbances. NMS has not been associated with Takotsubo cardiomyopathy (TCM). TCM is an abnormal response to physiological stressors resulting from the autonomic abnormalities which at times can mimic myocardial infarction (MI). We present a unique case of a 54-year-old female with bipolar disease presenting with lithium and haloperidol-induced NMS complicated by TCM. The purpose of this case is to make clinicians aware of this rare association.

Keywords: Cardiomyopathy; cardiovascular medicine; heart failure.

Publication types

Case Reports