Quantitative Assessment of Parenchymal Involvement Using 3D Lung Model in Adolescent With Covid-19 Interstitial Pneumonia

Luca Borro; Paolo Ciliberti; Teresa Pia Santangelo; Andrea Magistrelli; Andrea Campana; Francesca Calò Carducci; Marabotto Caterina; Paolo Tomà; Aurelio Secinaro

doi:10.3389/fped.2020.00453

Quantitative Assessment of Parenchymal Involvement Using 3D Lung Model in Adolescent With Covid-19 Interstitial Pneumonia

Front Pediatr. 2020 Aug 5:8:453. doi: 10.3389/fped.2020.00453. eCollection 2020.

Authors

Luca Borro¹, Paolo Ciliberti², Teresa Pia Santangelo¹, Andrea Magistrelli¹, Andrea Campana³, Francesca Calò Carducci⁴, Marabotto Caterina⁵, Paolo Tomà¹, Aurelio Secinaro¹

Affiliations

¹ Department of Imaging, Bambino Gesù Children's Hospital IRCSS, Rome, Italy.
² Pediatric Cardiology and Pediatric Cardiac Surgery Department, Bambino Gesù Children's Hospital IRCSS, Rome, Italy.
³ Department of Pediatric Medicine, Bambino Gesù Children's Hospital, Rome, Italy.
⁴ Pediatric University Hospital-Department, Bambino Gesù Children's Hospital, Rome, Italy.
⁵ Unit of General Pediatrics and Pediatric Infectious Diseases, Bambino Gesù Children's Hospital, Rome, Italy.

Abstract

Background: Amount of parenchymal involvement in patients with interstitial pneumonia Covid-19 related, seems to be associated with a worse prognosis. Nowadays 3D reconstruction imaging is expanding its role in clinical medical practice. We aimed to use 3D lung reconstruction of a young lady affected by Sars-CoV2 infection and interstitial pneumonia, to better visualize, and quantitatively assess the parenchymal involvement. Methods: Volumetric Chest CT scan was performed in a 15 years old girl with interstitial lung pneumonia, Sars-CoV2 infection related. 3D modeling of the lungs, with differentiation of healthy and affected parenchymal area were obtained by using multiple software. Results: 3D reconstruction imaging allowed us to quantify the lung parenchyma involved, Self-explaining 3D images, useful for the understanding, and discussion of the clinical case were also obtained. Conclusions: Quantitative Assessment of Parenchymal Involvement Using 3D Lung Model in Covid-19 Infection is feasible and it provides information which could play a role in the management and risk stratification of these patients.

Keywords: 3D in Covid19; 3D lung reconstructions; 3D modeling in pneumonia; 3D parenchima reconstruction; 3D quantify in pneumonia; 3D rendering in pneumonia.