Four SARS-CoV-2 Genome Sequences from Late April in Stockholm, Sweden, Reveal a Rare Mutation in the Spike Protein

Tatiany Aparecida Teixeira Soratto; Hamid Darban; Annelie Bjerkner; Maarten Coorens; Jan Albert; Tobias Allander; Björn Andersson

doi:10.1128/MRA.00934-20

Four SARS-CoV-2 Genome Sequences from Late April in Stockholm, Sweden, Reveal a Rare Mutation in the Spike Protein

Microbiol Resour Announc. 2020 Aug 27;9(35):e00934-20. doi: 10.1128/MRA.00934-20.

Authors

Tatiany Aparecida Teixeira Soratto^{1

2}, Hamid Darban³, Annelie Bjerkner⁴, Maarten Coorens⁵, Jan Albert^{4

5}, Tobias Allander^{4

5}, Björn Andersson³

Affiliations

¹ Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden tsoratto@gmail.com.
² Department of Microbiology, Immunology, and Parasitology, Federal University of Santa Catarina, Florianopólis, Santa Catarina, Brazil.
³ Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
⁴ Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
⁵ Department of Clinical Microbiology, Karolinska University Hospital, Stockholm, Sweden.

Abstract

Here, we report four coding-complete severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome sequences from Stockholm, Sweden, sampled in late April 2020. A rare variant at bp 23463 of the SARS-CoV-2 genome was found, which corresponds to the S1 subunit of the spike protein, changing an arginine (R) residue to histidine (H).