Clinical characteristics of moderate and severe cases with COVID-19 in Wuhan, China: a retrospective study

Clin Exp Med. 2021 Feb;21(1):35-39. doi: 10.1007/s10238-020-00662-z. Epub 2020 Sep 19.

Abstract

With the outbreak of COVID-19 ongoing, this infectious disease has been posing a significant threat to public health. However, we are still relatively inexperienced on recognizing the clinical characteristics of severe COVID-19 and death cases. Therefore, we hereby collected and analyzed a total of 232 cases to illustrate the clinical characteristics of such patients in Wuhan and to find notable marks for early clinical warning. We consider age, comorbidities, platelet count, albumin, D-dimer, LDH, CRP and IL-6 level might be more meaningful marks for COVID-19 prognostic evaluation.

Keywords: COVID-19; Clinical characteristics; SARS-cov-2.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Blood Cell Count
  • Blood Chemical Analysis
  • COVID-19 / epidemiology
  • COVID-19 / etiology*
  • COVID-19 / mortality
  • China / epidemiology
  • Comorbidity
  • Humans
  • Inflammation / blood
  • Inflammation / virology
  • Intensive Care Units
  • Interleukin-6 / blood
  • Middle Aged
  • Retrospective Studies

Substances

  • IL6 protein, human
  • Interleukin-6