Spontaneous community-acquired bacterial meningitis in adults admitted to the intensive care units in the Caribbean French West Indies: Unusual prevalence of Klebsiella pneumonia

Pascale Piednoir; Ulrich Clarac; Amélie Rolle; Sylvaine Bastian; Gaelle Gruel; Frédéric Martino; Hossein Mehdaoui; Marc Valette; Sébastien Breurec; Michel Carles

doi:10.1016/j.ijid.2020.09.1420

Spontaneous community-acquired bacterial meningitis in adults admitted to the intensive care units in the Caribbean French West Indies: Unusual prevalence of Klebsiella pneumonia

Int J Infect Dis. 2020 Nov:100:473-475. doi: 10.1016/j.ijid.2020.09.1420. Epub 2020 Sep 22.

Authors

Affiliations

¹ Réanimation Polyvalente, CHU de la Guadeloupe 97139 Les Abymes, Guadeloupe, France.
² Laboratoire de Microbiologie Clinique et Environnementale, CHU Guadeloupe 97139 Les Abymes, Guadeloupe, France.
³ Unité Transmission, Réservoir et Diversité des Pathogènes, Institut Pasteur de Guadeloupe, Les Abymes, Guadeloupe, France.
⁴ Service de Réanimation Polyvalente, CHU de Martinique 97261 Fort-de-France, Martinique, France.
⁵ Unité Transmission, Réservoir et Diversité des Pathogènes, Institut Pasteur de Guadeloupe, Les Abymes, Guadeloupe, France; Faculté de Médecine Hyacinthe Bastaraud, Université des Antilles, Pointe-à-Pitre, Guadeloupe, France; Centre d'Investigation Clinique 1424 INSERM, Pointe-à-Pitre/Les Abymes, Guadeloupe, France.
⁶ Réanimation Polyvalente, CHU de la Guadeloupe 97139 Les Abymes, Guadeloupe, France; Faculté de Médecine Hyacinthe Bastaraud, Université des Antilles, Pointe-à-Pitre, Guadeloupe, France; Universite Cote d'Azur, INSERM, C3M, Nice, Martinique, France. Electronic address: michel.carles@chu-guadeloupe.fr.

PMID: 32976993
DOI: 10.1016/j.ijid.2020.09.1420

Abstract

An unusual prevalence of Klebsiella pneumoniae (24%) was observed in 25 adults admitted to the intensive care units of two University Hospitals in the French West Indies, for spontaneous community-acquired bacterial meningitis. All tested isolates had several prominent features of hypervirulent isolates, including rmpa and iuc genes, K1 or K2 capsular serotypes.

Keywords: Epidemiology; Klebsiella pneumonia; Meningitis; Virulence.

MeSH terms

Aged
Bacterial Proteins / genetics
Bacterial Proteins / metabolism
Community-Acquired Infections / epidemiology
Community-Acquired Infections / microbiology*
Female
Humans
Intensive Care Units / statistics & numerical data
Klebsiella Infections / epidemiology
Klebsiella Infections / microbiology*
Klebsiella pneumoniae / genetics
Klebsiella pneumoniae / isolation & purification*
Klebsiella pneumoniae / metabolism
Klebsiella pneumoniae / pathogenicity
Male
Meningitis, Bacterial / epidemiology
Meningitis, Bacterial / microbiology*
Middle Aged
Pneumonia / epidemiology
Pneumonia / microbiology*
Prevalence
Virulence
West Indies / epidemiology

Substances

Bacterial Proteins