Genetic Contributions to Acquired Epilepsies

Epilepsy Curr. 2021 Jan-Feb;21(1):5-13. doi: 10.1177/1535759720954254. Epub 2020 Sep 29.

Abstract

Whether genetic factors contribute to acquired epilepsies has long been controversial. Supporters observe that, among individuals exposed to seemingly the same brain insult, only a minority develops unprovoked seizures. Yet, only in relatively recent years have studies started to build a case for genetic contributions. Here, we appraise this emerging evidence, by providing a critical review of studies published in the field.

Keywords: acquired epilepsy; family history; genetics; post-traumatic epilepsy; poststroke epilepsy.