Should modern molecular testing be routinely available for the diagnosis of musculoskeletal infection?

S-T Jerry Tsang; David W Eyre; Bridget L Atkins; A Hamish R W Simpson

doi:10.1302/0301-620X.102B10.BJJ-2020-1496

Should modern molecular testing be routinely available for the diagnosis of musculoskeletal infection?

Bone Joint J. 2020 Oct;102-B(10):1274-1276. doi: 10.1302/0301-620X.102B10.BJJ-2020-1496.

Authors

S-T Jerry Tsang^{1

2}, David W Eyre^{3

4}, Bridget L Atkins⁵, A Hamish R W Simpson¹

Affiliations

¹ Department of Orthopaedic Surgery, University of Edinburgh, Edinburgh, UK.
² Department of Trauma and Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh, UK.
³ Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
⁴ NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.
⁵ Bone Infection Unit, Nuffield Orthopaedic Hospital, Department of Microbiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

PMID: 32993334
DOI: 10.1302/0301-620X.102B10.BJJ-2020-1496

No abstract available

Keywords: Culture-negative infection; Fracture-related infection; Metagenomic sequencing; Molecular diagnostics; Musculoskeletal infection; Next-generation sequencing; Prosthetic joint infection.

Publication types

Editorial

MeSH terms

Bacterial Infections / diagnosis*
Bacterial Infections / microbiology
DNA, Bacterial / analysis*
Humans
Musculoskeletal Diseases / diagnosis*
Musculoskeletal Diseases / microbiology

Substances

DNA, Bacterial