[Severe skin and soft tissue infections. An update]

Medicina (B Aires). 2020;80(5):531-540.
[Article in Spanish]

Abstract

Severe skin and soft tissue infections present a high morbidity and mortality and require a complex surgical treatment. Its estimated annual incidence is 0.3 to 5 cases per 10 000 people. The most common etiologic agents are Streptococcus pyogenes, Staphylococcus aureus, anaerobes and gram-negative bacilli. A prompt diagnosis and the timely initiation of an empirical antibiotic scheme and repeated surgical debridement can avert a worrisome outcome. New therapeutic options are promising, especially for infections caused by multidrug resistant germs. A multidisciplinary approach is fundamental for the correct management of these conditions.

Las infecciones graves de piel y partes blandas presentan una elevada morbimortalidad y requieren un complejo tratamiento quirúrgico. Su incidencia anual está estimada en 0.3 a 5 casos por 10 000 personas. Los agentes etiológicos más comunes son Streptococcus pyogenes, Staphylococcus aureus, anaerobios y bacilos Gram negativos. El diagnóstico precoz y el tratamiento oportuno, tanto empírico antibiótico como quirúrgico, determinan el pronóstico. Existen nuevas opciones terapéuticas para estas infecciones, especialmente las producidas por gérmenes multirresistentes. Un enfoque terapéutico multidisciplinario es fundamental para su correcto manejo.

Keywords: cellulitis; diagnosis; fasciitis; myositis; treatment.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Skin Diseases, Bacterial / diagnosis
  • Skin Diseases, Bacterial / therapy
  • Soft Tissue Infections / diagnosis*
  • Soft Tissue Infections / therapy
  • Staphylococcal Infections / drug therapy
  • Streptococcus pyogenes

Substances

  • Anti-Bacterial Agents