Double trouble: Extrauterine epithelioid trophoblastic tumor with uterine choriocarcinoma - An autopsy report

Indian J Cancer. 2020 Oct-Dec;57(4):463-466. doi: 10.4103/ijc.IJC_220_19.

Abstract

Gestational trophoblastic tumors (GTTs) include choriocarcinoma, epithelioid trophoblastic tumor, and placental site trophoblastic tumor. The occurrence of mixed GTT is rare. We report such a case in a 24-year-old woman who presented with menorrhagia since 2 months and obstetric history of two abortions, one of which was a molar pregnancy. She was undergoing evaluation for carcinoma cervix and treatment for pulmonary tuberculosis from another hospital when she was admitted at our institute for further workup and treatment. However, she succumbed and an autopsy was performed. Histologic evaluation after the autopsy revealed uterine choriocarcinoma with metastatic epithelioid trophoblastic tumor (ETT) in the lung and spleen.

Keywords: Dual malignancy; Gestational trophoblastic tumor; dual pathology; post-mortem.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autopsy
  • Choriocarcinoma / complications
  • Choriocarcinoma / pathology*
  • Choriocarcinoma / surgery
  • Female
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / secondary*
  • Lung Neoplasms / surgery
  • Neoplasms, Glandular and Epithelial / complications
  • Neoplasms, Glandular and Epithelial / secondary*
  • Neoplasms, Glandular and Epithelial / surgery
  • Pregnancy
  • Prognosis
  • Splenic Neoplasms / complications
  • Splenic Neoplasms / secondary*
  • Splenic Neoplasms / surgery
  • Trophoblastic Neoplasms / complications
  • Trophoblastic Neoplasms / secondary*
  • Trophoblastic Neoplasms / surgery
  • Uterine Neoplasms / complications
  • Uterine Neoplasms / pathology*
  • Uterine Neoplasms / surgery
  • Young Adult