Resistance-Conferring Mycobacterial Mutations and Quantification of Early Bactericidal Activity

Am J Respir Crit Care Med. 2021 Mar 1;203(5):635-637. doi: 10.1164/rccm.202007-2740LE.

Authors

Solomon P le Roux¹, Caryn Upton¹, Naadira Vanker¹, Kelly E Dooley², Andreas H Diacon³; A5312 Study Team

Collaborators

A5312 Study Team:
Sachiko Miyahara, Florian von Groote-Bidlingmaier, Xin Sun, Richard Hafner, Susan L Rosenkranz, Elisa H Ignatius, Eric L Nuermberger, Laura Moran, Kathleen Donahue, Susan Swindells, Rachel Issa, Christopher Lane, Mark Lojacono, Rachel Mahachi, William Murtaugh, Lynette Purdue, Akbar Shahkolahi, Ronald Ssenyonga

Affiliations

¹ TASK Applied Science Cape Town, South Africa.
² Johns Hopkins University Baltimore, Maryland and.
³ TASK Applied Science and Stellenbosch University Cape Town, South Africa.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Comment

MeSH terms

Antitubercular Agents
Humans
Isoniazid
Mutation / genetics
Mycobacterium tuberculosis* / genetics
Tuberculosis, Multidrug-Resistant*

Substances

Antitubercular Agents
Isoniazid

Grants and funding