"Preventive treatment of disease" is one of the characteristics and advantages of traditional Chinese medicine. It is the most influential theory of traditional Chinese medicine. The core of the theory is "pre-prevention before disease", "prevention of disease from progress" and "prevention of recovery after disease", and the prevention concepts are "prevention of disease from deve-lopment" and "blockage and reversal". Based on the analysis of large numbers of ancient books, we put forward the overall pharmacovigilance theoretical frame that is composed of toxicity cognition, application, prevention and detoxification. With rich prospective prevention, the pharmacovigilance theory of traditional Chinese medicine was the essence of drug use experience in China for thousands of years. It coincides with the idea of preventing disease with precautions and preventing the occurrence of drug-induced diseases. This article intends to consider the theory and practice of pharmacovigilance of Chinese medicine from the "preventive treatment of disease", in order to provide reference for clinical safety medication. It has puts forward the practical measures of pharmacovigilance of traditional Chinese medicine, such as giving medical advice, paying attention to monitoring, preventing biological change, planning for the long term, preventing disease from changing, delaying the disease progress, protecting vital Qi, controlling internal disorder and preventing recurrence. It also indicated that pharmacovigilance of traditional Chinese medicine is an important part of the "preventive treatment of disease", and an important guarantee for the safe and rational use of medicines in clinical practice, which is conducive to protecting and promoting people's health and improving people's quality of life.
Keywords: pharmacovigilance; preventive treatment of disease; safe; traditional Chinese medicine.