Interventions on patent ductus arteriosus and its impact on congenital heart disease

Cardiol Young. 2020 Nov;30(11):1566-1571. doi: 10.1017/S1047951120004126. Epub 2020 Nov 23.

Abstract

The ductus arteriosus (DA) connects the pulmonary artery to the aorta to bypass the pulmonary circulation in utero. It normally closes within 24-72 hours after birth due to increased pulmonary resistance from an increase in oxygen partial pressure with the baby's first breath. Medical treatment can help close the DA in certain situations where closure is delayed. However, in duct-dependent cardiac defects, the presence of the DA is crucial for survival and as such medical and surgical techniques have evolved to prevent closure. This review aims to outline the two main management options for keeping a ductus arteriosus patent. This includes stenting the PDA and shunting via a modified Blalock-Taussig shunt. Whilst both techniques exist, multicentre trials have found equal mortality end points but significantly reduced morbidity with stenting than shunting. This is also reflected by shorter recovery times, reduced requirement for extracorporeal membrane oxygenation (ECMO), and improved quality of life, although stent longevity remains a limiting factor.

Keywords: Surgery; aorta; aortic dissection; dissection.

Publication types

  • Review

MeSH terms

  • Blalock-Taussig Procedure*
  • Cardiac Catheterization
  • Ductus Arteriosus* / diagnostic imaging
  • Ductus Arteriosus* / surgery
  • Ductus Arteriosus, Patent* / surgery
  • Heart Defects, Congenital*
  • Humans
  • Infant
  • Quality of Life