Characteristics of Adults Aged 18-49 Years Without Underlying Conditions Hospitalized With Laboratory-Confirmed Coronavirus Disease 2019 in the United States: COVID-NET-March-August 2020

Daniel Owusu; Lindsay Kim; Alissa O'Halloran; Michael Whitaker; Alexandra M Piasecki; Arthur Reingold; Nisha B Alden; Amber Maslar; Evan J Anderson; Patricia A Ryan; Sue Kim; Kathryn Como-Sabetti; Emily B Hancock; Alison Muse; Nancy M Bennett; Laurie M Billing; Melissa Sutton; H Keipp Talbot; Jake Ortega; Lynnette Brammer; Alicia M Fry; Aron J Hall; Shikha Garg; COVID-NET Surveillance Teama

doi:10.1093/cid/ciaa1806

Characteristics of Adults Aged 18-49 Years Without Underlying Conditions Hospitalized With Laboratory-Confirmed Coronavirus Disease 2019 in the United States: COVID-NET-March-August 2020

Clin Infect Dis. 2021 Mar 1;72(5):e162-e166. doi: 10.1093/cid/ciaa1806.

Authors

Daniel Owusu^{1

2}, Lindsay Kim^{1

3}, Alissa O'Halloran¹, Michael Whitaker¹, Alexandra M Piasecki^{1

4}, Arthur Reingold^{5

6}, Nisha B Alden⁷, Amber Maslar⁸, Evan J Anderson^{9

10}, Patricia A Ryan¹¹, Sue Kim¹², Kathryn Como-Sabetti¹³, Emily B Hancock¹⁴, Alison Muse¹⁵, Nancy M Bennett¹⁶, Laurie M Billing¹⁷, Melissa Sutton¹⁸, H Keipp Talbot¹⁹, Jake Ortega²⁰, Lynnette Brammer¹, Alicia M Fry^{1

3}, Aron J Hall¹, Shikha Garg^{1

3}; COVID-NET Surveillance Teama

Collaborators

COVID-NET Surveillance Teama:
Charisse N Cummings, Rachel Holstein, Anita Kambhampati, Seth Meador, Jonathan M Wortham, Shua J Chai, Breanna Kawasaki, Kimberly Yousey-Hindes, Kyle P Openo, Maya L Monroe, Libby Reeg, Ruth Lynfield, Nancy Eisenberg, Grant R Barney, Christina B Felsen, Jessica Shiltz, Nicole West, William Schaffner, Andrea Price

Affiliations

¹ CDC COVID-NET Team.
² Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
³ US Public Health Service, Rockville, Maryland, USA.
⁴ Cherokee Nation Assurance, Arlington, Virginia, USA.
⁵ California Emerging Infections Program, Oakland, California, USA.
⁶ School of Public Health, University of California, Berkeley, Berkeley, California, USA.
⁷ Colorado Department of Public Health and Environment, Denver, Colorado, USA.
⁸ Connecticut Emerging Infections Program, Yale School of Public Health, New Haven, Connecticut, USA.
⁹ Departments of Pediatrics and Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
¹⁰ Emerging Infections Program, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA.
¹¹ Maryland Department of Health, Baltimore, Maryland, USA.
¹² Michigan Department of Health and Human Services, Lansing, Michigan, USA.
¹³ Minnesota Department of Health, St. Paul, Minnesota, USA.
¹⁴ New Mexico Emerging Infections Program, Santa Fe, New Mexico, USA.
¹⁵ New York State Department of Health, Albany, New York, USA.
¹⁶ University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
¹⁷ Ohio Department of Health, Columbus, Ohio, USA.
¹⁸ Oregon Health Authority, Portland, Oregon, USA.
¹⁹ Vanderbilt University Medical Center, Nashville, Tennessee, USA.
²⁰ Salt Lake County Health Department, Salt Lake City, Utah, USA.

Abstract

Among 513 adults aged 18-49 years without underlying medical conditions hospitalized with coronavirus disease 2019 (COVID-19) during March 2020-August 2020, 22% were admitted to an intensive care unit, 10% required mechanical ventilation, and 3 patients died (0.6%). These data demonstrate that healthy younger adults can develop severe COVID-19.

Keywords: COVID-19; COVID-NET; SARS-CoV-2; hospitalization; young adults.

Published by Oxford University Press for the Infectious Diseases Society of America 2020.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
COVID-19*
Hospitalization
Humans
Intensive Care Units
Laboratories
Middle Aged
SARS-CoV-2
United States / epidemiology
Young Adult