Frontal Fibrosing Alopecia and Autoimmune Disorders in a Hispanic Female

Skin Appendage Disord. 2020 Nov;6(6):362-365. doi: 10.1159/000507557. Epub 2020 Aug 26.

Abstract

Frontal fibrosing alopecia (FFA) is a cicatricial alopecia characterized by hairline recession. Multiple autoimmune pathologies have been reported in patients with FFA. Despite the fact that FFA etiology remains unknown, there has been described an association with autoimmune disorders probably caused by an altered activity of cytotoxic CD8 T lymphocytes. Moreover, other autoimmune pathologies develop TH1 and TH17 response. Genetics could be responsible, in part, for the role of multiple simultaneous autoimmune disorders. Herein, we describe a case of a female patient with vitiligo, lichen sclerosus, and autoimmune hypothyroidism who developed a pruritic band-like recession of the frontal hairline. More research is needed in this area since autoimmune events in these patients may not be a mere coincidence.

Keywords: Autoimmune disease; Dyschromia; Frontal fibrosing alopecia; Hypopigmentation; Vitiligo.

Publication types

  • Case Reports