Atypical cellular neurothekeoma (ACN) of the elderly: case report and brief review of the literature

Nicoletta D'Alessandris; Andrea Picchetto; Maria Gemma Pignataro; Bruna Cerbelli; Domenico Manzo; Carlo Della Rocca; Giulia d'Amati; Angelina Pernazza

doi:10.32074/1591-951X-104

Atypical cellular neurothekeoma (ACN) of the elderly: case report and brief review of the literature

Pathologica. 2020 Dec;112(4):210-213. doi: 10.32074/1591-951X-104.

Authors

Nicoletta D'Alessandris¹, Andrea Picchetto², Maria Gemma Pignataro¹, Bruna Cerbelli¹, Domenico Manzo³, Carlo Della Rocca⁴, Giulia d'Amati¹, Angelina Pernazza⁴

Affiliations

¹ Department of Radiological, Oncological and Pathological Sciences, Sapienza, University of Rome, Rome, Italy.
² Department of General Surgery and Surgical Specialties "P. Stefanini", Sapienza University of Rome, Rome, Italy.
³ General Surgery Division, Raphael Medical, Rome, Italy.
⁴ Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino-Sapienza University, Latina, Italy.

Abstract

Atypical cellular neurothekeoma (ACN) is an aggressive and rare variant of cellular neurothekeoma. Only few cases have been reported in the literature and the biological behavior seems to be uncertain. We describe the case of an ACN presenting on the scalp of an elderly man, emphasizing the cytologic features of malignancy. In addition, we provide a brief overview of the literature and discuss the differential diagnosis with other entities, and the possible diagnostic pitfalls.

Keywords: atypical cellular neurothekeoma; diagnostic pitfalls; scalp elderly.

Publication types

Case Reports

MeSH terms

Aged
Biomarkers, Tumor / analysis
Diagnosis, Differential
Humans
Immunohistochemistry
Male
Neurothekeoma* / diagnosis
Neurothekeoma* / pathology
Scalp / pathology*
Skin Neoplasms / diagnosis
Skin Neoplasms / pathology
Soft Tissue Neoplasms / diagnosis
Soft Tissue Neoplasms / pathology

Substances

Biomarkers, Tumor