Tocilizumab did not reduce hypoxemic respiratory failure or death in hospitalized patients with COVID-19

Ann Intern Med. 2021 Feb;174(2):JC16. doi: 10.7326/ACPJ202102160-016. Epub 2021 Feb 2.

Abstract

Stone JH, Frigault MJ, Serling-Boyd NJ, et al. Efficacy of tocilizumab in patients hospitalized with Covid-19. N Engl J Med. 2020;383:2333-44. 33085857.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Antibodies, Monoclonal, Humanized / therapeutic use*
  • COVID-19 / mortality
  • COVID-19 Drug Treatment*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multicenter Studies as Topic
  • Randomized Controlled Trials as Topic
  • Respiratory Insufficiency / drug therapy*
  • Respiratory Insufficiency / mortality
  • Respiratory Insufficiency / virology
  • SARS-CoV-2

Substances

  • Antibodies, Monoclonal, Humanized
  • tocilizumab