Predictors of starting antimicrobial treatment in patients with nontuberculous mycobacterial lung disease in the Italian scenario: A SITA GIOVANI-IRENE promoted web-survey

Respir Med. 2021 Apr:179:106341. doi: 10.1016/j.rmed.2021.106341. Epub 2021 Feb 15.

Abstract

The disease burden due to nontuberculous mycobacteria is growing worldwide, consequently to improved diagnostic abilities and an increase in the individuals at risk. Uncertainties exist about the right moment on which start treatment. We investigated the clinical features associated with starting an antimicrobial treatment in patients with nontuberculous mycobacterial lung disease among Italian physicians involved in the field. We found that in real life predictors of starting antimicrobial treatment are quite adherent to international guidelines, with some uncertainties regarding the implication of immunosuppressive drugs.

Keywords: Antimycobacterial treatment; Clinical management; Lung disease; Nontuberculous mycobacteria.

MeSH terms

  • Anti-Bacterial Agents / administration & dosage*
  • Guideline Adherence*
  • Humans
  • Immunosuppressive Agents
  • Italy
  • Mycobacterium Infections, Nontuberculous*
  • Physicians
  • Pneumonia, Bacterial / drug therapy*
  • Pneumonia, Bacterial / microbiology*
  • Practice Guidelines as Topic*

Substances

  • Anti-Bacterial Agents
  • Immunosuppressive Agents