Contemporaneous Risk Factors for Visual Acuity in Non-Infectious Uveitis

Ocul Immunol Inflamm. 2021 Aug 18;29(6):1056-1063. doi: 10.1080/09273948.2020.1828493. Epub 2021 Feb 23.

Abstract

Introduction: We evaluated the associations of clinical and demographic characteristics with visual acuity (VA) with over 5 years in a subspecialty noninfectious uveitis population.

Methods: Retrospective data from 5,530 noninfectious uveitis patients were abstracted by expert reviewers, and contemporaneous associations of VA with demographic and clinical factors were modeled.

Results: Patients were a median of 41 years old, 65% female, and 73% white. Eyes diagnosed ≥5 years prior to cohort entry had worse VA (-1.2 lines) than those diagnosed <6 months prior, and eyes with cataract surgery performed prior to entry had worse VA (-5.9 lines) than those performed during follow-up. Vitreous haze (-4.2 lines for 3+ vs quiet), hypotony (-2.5 lines for ≤5 mm Hg vs 6-23 mm Hg), and CNV (-1.8 lines) all were strongly associated with reduced VA.

Conclusion: Factors associated with reduced VA included well-known structural complications, and lack of subspecialty care during cataract surgery.

Keywords: Visual Acuity; risk Factors; uveitis.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cataract Extraction
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Factors
  • Uveitis / physiopathology*
  • Vision Disorders / physiopathology*
  • Visual Acuity / physiology*
  • Young Adult