Keywords: 55 serological assays have received EUA. Nonetheless; COVID-19; SARS-CoV-2; The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 was met with a rapid introduction of commercially available serological assays for SARS-CoV-2 antibody detection. Soon after being declared an emergency in the US; as laboratories gained access to this unprecedented number of assays; exceeding the number of assays available for any other infectious disease and most other laboratory analytes. As a result of this rapid expansion and at times dubious quality; hundreds of serological assays for SARS-CoV-2 were introduced; serology; the Food and Drug Administration (FDA) began reviewing and regulating all SARS-CoV-2 serological assays under emergency use authorization (EUA). To date; the utility of SARS-CoV-2 serological testing remained unclear.