Positive SARS-CoV-2 RNA with Significant Inflammatory State and Thrombophilia after 12 Weeks of Initial Diagnosis of COVID-19 Infection

Manuel Francisco Betancourt; Kimberly Michelle Grant; James Scott Johnson; Dhanashree S Kelkar; Kamal Sharma

doi:10.4103/jgid.jgid_286_20

Positive SARS-CoV-2 RNA with Significant Inflammatory State and Thrombophilia after 12 Weeks of Initial Diagnosis of COVID-19 Infection

J Glob Infect Dis. 2021 Feb 26;13(1):42-43. doi: 10.4103/jgid.jgid_286_20. eCollection 2021 Jan-Mar.

Authors

Manuel Francisco Betancourt¹, Kimberly Michelle Grant¹, James Scott Johnson¹, Dhanashree S Kelkar², Kamal Sharma³

Affiliations

¹ Department of Critical Care Medicine, BayCare Winter Haven Hospital, Jacksonville, Florida, USA.
² Department of Emergency Medicine, University of Florida, Jacksonville, Florida, USA.
³ Department of Hematology, BayCare Winter Haven Hospital, Jacksonville, Florida, USA.

Abstract

The ongoing COVID-19 pandemic has affected most countries in the world, with significant economic and public health implications. There is rising concern that patients who recover from COVID-19 may be at risk of reinfection. Another potential concern is the uncommon clinical scenario of a patient having persistent SARS-CoV-2 RNA test over 3 months after the initial COVID-19 infection, as the patient presented. Whether presenting as a long-term infection (12 weeks) or reinfection, patients with COVID-19 will continue to have a severe inflammatory and prothrombotic state that could carry potential life-threatening thrombosis.

Keywords: COVID-19; SARS-CoV-2; pandemic; reinfection; thrombophilia.

Publication types

Case Reports