Advancing early gastric cancer detection

FEBS Open Bio. 2021 Jul;11(7):1812-1813. doi: 10.1002/2211-5463.13217.

Abstract

Important factors in combating cancer are early detection and accurate assessment of the best course of treatment. In a study published in this issue, Wang et al. identify possible miRNA biomarkers for improved determination of gastric cancer stage and prognosis. In particular, they show increased miR-194 levels are a predictor of more favourable gastric cancer prognosis, at least in part due to miR-194 downregulating production of a key protein for cancer development: CCND1.

Keywords: biomarker; gastric cancer; miR-194; miRNA; prognosis; the cancer genome atlas.

Publication types

  • Comment

MeSH terms

  • Biomarkers, Tumor / genetics
  • Early Detection of Cancer
  • Humans
  • MicroRNAs* / genetics
  • Stomach Neoplasms* / diagnosis
  • Stomach Neoplasms* / genetics

Substances

  • Biomarkers, Tumor
  • MicroRNAs