Clinical and genetic features of Epstein-Barr virus-triggered late-onset primary hemophagocytic lymphohistiocytosis: Ten pedigrees study

Clin Transl Med. 2021 Jun;11(6):e393. doi: 10.1002/ctm2.393.

Authors

Lili Gao¹, Li Yang¹, Liang Huang¹, Yi Xiao¹, Jinniu Deng¹, Miao Zheng¹, Hui Luo¹, Lijun Jiang¹, Min Xiao¹, Chunrui Li¹, Jianfeng Zhou¹

Affiliation

¹ Department of Hematology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

No abstract available

Keywords: Epstein-Barr virus (EBV); genetic features; late-onset primary hemophagocytic lymphohistiocytosis; pedigree investigation.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Aged, 80 and over
Biomarkers, Tumor / genetics*
Child
Epstein-Barr Virus Infections / complications*
Epstein-Barr Virus Infections / virology
Female
Follow-Up Studies
Gene Expression Profiling
Gene Expression Regulation, Neoplastic*
Hematopoietic Stem Cell Transplantation
Herpesvirus 4, Human / isolation & purification*
Humans
Infant
Lymphohistiocytosis, Hemophagocytic / etiology
Lymphohistiocytosis, Hemophagocytic / genetics
Lymphohistiocytosis, Hemophagocytic / pathology*
Lymphohistiocytosis, Hemophagocytic / therapy
Male
Middle Aged
Pedigree
Prognosis
Retrospective Studies
Survival Rate
Young Adult

Substances

Biomarkers, Tumor