New Designer Drugs

Emerg Med Clin North Am. 2021 Aug;39(3):677-687. doi: 10.1016/j.emc.2021.04.013. Epub 2021 Jun 9.

Abstract

In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and others. Kratom, a plant occasionally used for opiate detoxification, along with the sedatives etizolam and phenibut, will be discussed. Lastly, this article discusses the phenethylamines and marijuana.

Keywords: Novel drugs; Opiates; Overdose; Phenethylamine; Toxicology.

Publication types

  • Review

MeSH terms

  • Analgesics, Opioid / administration & dosage
  • Analgesics, Opioid / adverse effects
  • Buprenorphine / administration & dosage
  • Buprenorphine / adverse effects
  • Cannabinoids / adverse effects
  • Designer Drugs / administration & dosage
  • Designer Drugs / adverse effects*
  • Drug Overdose / drug therapy
  • Fentanyl / administration & dosage
  • Fentanyl / adverse effects
  • Humans
  • Hypnotics and Sedatives / administration & dosage
  • Hypnotics and Sedatives / adverse effects
  • Illicit Drugs / adverse effects*
  • Loperamide / administration & dosage
  • Loperamide / adverse effects
  • Mitragyna / adverse effects
  • Naloxone / therapeutic use
  • Narcotic Antagonists / therapeutic use
  • Phenethylamines / adverse effects
  • Substance-Related Disorders / complications*

Substances

  • Analgesics, Opioid
  • Cannabinoids
  • Designer Drugs
  • Hypnotics and Sedatives
  • Illicit Drugs
  • Narcotic Antagonists
  • Phenethylamines
  • Naloxone
  • Buprenorphine
  • Loperamide
  • Fentanyl