An outbreak caused by the SARS-CoV-2 Delta (B.1.617.2) variant in a care home after partial vaccination with a single dose of the COVID-19 vaccine Vaxzevria, London, England, April 2021

Euro Surveill. 2021 Jul;26(27):2100626. doi: 10.2807/1560-7917.ES.2021.26.27.2100626.

Abstract

We investigated a COVID-19 outbreak of the SARS-CoV-2 Delta variant of concern in a London care home, where 8/21 residents and 14/21 staff had received a single dose of Vaxzevria (ChAdOx1-S; AstraZeneca) vaccine. We identified 24 SARS-CoV-2 infections (16 residents, 8 staff) among 40 individuals (19 residents, 21 staff); four (3 residents, 1 staff) were hospitalised, and none died. The attack rate after one vaccine dose was 35.7% (5/14) for staff and 81.3% (13/16) for residents.

Keywords: B.1.617.2 variant; COVID-19; ChAdOx1 vaccine; Delta variant; SARS-CoV-2; Vaxzevria; care home outbreaks; vaccine effectiveness.

MeSH terms

  • COVID-19 Vaccines
  • COVID-19*
  • Disease Outbreaks
  • England
  • Humans
  • London / epidemiology
  • SARS-CoV-2*
  • Vaccination

Substances

  • COVID-19 Vaccines