A Practical Approach to the Diagnosis and Management of Classic Lichen Planopilaris

Am J Clin Dermatol. 2021 Sep;22(5):681-692. doi: 10.1007/s40257-021-00630-7. Epub 2021 Aug 4.

Abstract

Lichen planopilaris is a primary lymphocytic cicatricial alopecia that commonly presents with hair loss at the vertex or parietal scalp. Patients may also have associated scalp itching, burning or tenderness. Due to scarring, hair loss is typically permanent. The main goals of treatment are reducing symptoms and preventing disease progression and further hair loss. Currently, the literature has limited evidence on treatments for this difficult condition, and most available evidence is from case reports and case series. Furthermore, the evidence shows a varied response to therapy, with frequent reports of poor response. This article reviews the diagnosis of this rare disease, summarize the currently available treatments, and provide insights and practices from alopecia experts.

Publication types

  • Review

MeSH terms

  • Humans
  • Lichen Planus / diagnosis*
  • Lichen Planus / therapy*
  • Scalp / pathology
  • Scalp Dermatoses / diagnosis*
  • Scalp Dermatoses / pathology
  • Scalp Dermatoses / therapy*

Supplementary concepts

  • Lichen planus follicularis