Coronary artery revascularizations and cognitive decline - A systematic review

Curr Probl Cardiol. 2022 Oct;47(10):100960. doi: 10.1016/j.cpcardiol.2021.100960. Epub 2021 Aug 4.

Abstract

Coronary artery disease (CAD) is a risk factor for cognitive decline. The aim of this study was to systematically review recent literature on whether coronary artery revascularizations are associated to cognitive decline and dementia. Pubmed, Scopus, and CINAHL (EBSCO) were searched systematically from January 2009 to September 2020. Studies were conducted on persons with CAD undergoing coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) procedure compared to other coronary artery disease treatments, and the outcome was cognitive decline or dementia. Altogether four of the 680 reviewed articles met inclusion criteria. Results were inconsistent, and the outcome measurements heterogeneous between studies. Our findings indicate an evidence gap in the current understanding of long-term outcomes following coronary artery revascularization. However, evidence of long-term effects on cognition would complement our understanding of their benefits. There is a need for more studies on long-term cognitive outcomes after coronary artery revascularizations.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Cognitive Dysfunction*
  • Coronary Artery Disease*
  • Dementia*
  • Humans
  • Percutaneous Coronary Intervention*
  • Treatment Outcome