Counting on You: How MHC Tetramers Revolutionized the Study of T Cell Memory and CD8⁺ T Cell Exhaustion

J Immunol. 2021 Sep 1;207(5):1225-1227. doi: 10.4049/jimmunol.2100533.

Authors

Thomas H Mann¹, Susan M Kaech²

Affiliations

¹ NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA.
² NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA skaech@salk.edu.

PMID: 34426517
DOI: 10.4049/jimmunol.2100533

No abstract available

Publication types

Editorial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
CD8-Positive T-Lymphocytes / immunology*
Cellular Senescence
Clonal Anergy
Histocompatibility Antigens Class I / metabolism*
Humans
Immunoassay / methods*
Immunologic Memory
Protein Binding
Protein Multimerization

Substances

Histocompatibility Antigens Class I