The South African Parkinson's Disease Study Collection

Zuné Jansen van Rensburg; Shameemah Abrahams; Devina Chetty; Kathryn Step; Debbie Acker; Carl J Lombard; Alexis Elbaz; Jonathan Carr; Soraya Bardien

doi:10.1002/mds.28828

The South African Parkinson's Disease Study Collection

Mov Disord. 2022 Jan;37(1):230-232. doi: 10.1002/mds.28828. Epub 2021 Oct 22.

Authors

Zuné Jansen van Rensburg¹, Shameemah Abrahams^{1

2}, Devina Chetty¹, Kathryn Step¹, Debbie Acker^{1

3}, Carl J Lombard^{4

5}, Alexis Elbaz⁶, Jonathan Carr^{2

3}, Soraya Bardien^{1

2}

Affiliations

¹ Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
² South African Medical Research Council/Stellenbosch University Genomics of Brain Disorders Research Unit, Cape Town, South Africa.
³ Division of Neurology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
⁴ Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
⁵ Biostatistics Unit, South African Medical Research Council, Cape Town, South Africa.
⁶ Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Team "Exposome, Heredity, Cancer and Health," CESP, Villejuif, France.

PMID: 34676912
DOI: 10.1002/mds.28828

Abstract

Parkinson's disease (PD) incidence is increasing in sub-Saharan Africa. We recruited 687 individuals with PD from different ancestral groups across South Africa. More Afrikaner Europeans had early-onset PD than other ancestral groups. More men had PD than women, with a younger age at onset for men (56 years).

Keywords: Parkinson's disease; South Africa; ancestral groups; environmental factors; study collection.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Age of Onset
Female
Humans
Male
Parkinson Disease* / epidemiology
South Africa / epidemiology
White People