Resilience of the respiratory microbiome in controlled adult RSV challenge study

Leah Cuthbertson; Phillip James; Maximillian S Habibi; Ryan S Thwaites; Allan Paras; Christopher Chiu; Peter J M Openshaw; William O C Cookson; Miriam F Moffatt

doi:10.1183/13993003.01932-2021

Resilience of the respiratory microbiome in controlled adult RSV challenge study

Eur Respir J. 2021 Dec 31;59(1):2101932. doi: 10.1183/13993003.01932-2021. Print 2022 Jan.

Authors

Leah Cuthbertson¹, Phillip James¹, Maximillian S Habibi¹, Ryan S Thwaites¹, Allan Paras¹, Christopher Chiu², Peter J M Openshaw¹, William O C Cookson¹, Miriam F Moffatt³

Affiliations

¹ National Heart and Lung Institute, Imperial College London, London, UK.
² Dept of Infectious Disease, Imperial College London, London, UK.
³ National Heart and Lung Institute, Imperial College London, London, UK m.moffatt@imperial.ac.uk.

Abstract

This study of healthy adults revealed no major changes in the bacterial community of the respiratory tracts following RSV inoculation, suggesting that the adult respiratory microbial community is resilient to viral perturbations https://bit.ly/3AwnMc8

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Animals
Humans
Lung
Mice
Mice, Inbred BALB C
Microbiota*
Respiratory Syncytial Virus Infections*
Respiratory Syncytial Virus, Human*
Respiratory System

Abstract

Publication types

MeSH terms

Grants and funding