A Neuroeconomics Approach to Obesity

Biol Psychiatry. 2022 May 15;91(10):860-868. doi: 10.1016/j.biopsych.2021.09.019. Epub 2021 Sep 29.

Abstract

Obesity is a heterogeneous condition that is affected by physiological, behavioral, and environmental factors. Value-based decision making is a useful framework for integrating these factors at the individual level. The disciplines of behavioral economics and reinforcement learning provide tools for identifying specific cognitive and motivational processes that may contribute to the development and maintenance of obesity. Neuroeconomics complements these disciplines by studying the neural mechanisms underlying these processes. We surveyed recent literature on individual decision characteristics that are most frequently implicated in obesity: discounting the value of future outcomes, attitudes toward uncertainty, and learning from rewards and punishments. Our survey highlighted both consistent and inconsistent behavioral findings. These findings underscore the need to examine multiple processes within individuals to identify unique behavioral profiles associated with obesity. Such individual characterization will inform future studies on the neurobiology of obesity as well as the design of effective interventions that are individually tailored.

Keywords: Behavioral economics; Decision making; Energy balance; Intertemporal choice; Reinforcement learning; Uncertainty.

Publication types

  • Review
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, N.I.H., Extramural

MeSH terms

  • Decision Making* / physiology
  • Humans
  • Neurobiology
  • Obesity
  • Reinforcement, Psychology
  • Reward*