Acute Eosinophilic Pneumonia Secondary to Daptomycin

Cureus. 2021 Nov 9;13(11):e19403. doi: 10.7759/cureus.19403. eCollection 2021 Nov.

Abstract

Daptomycin is an antimicrobial agent with activity against gram-positive bacteria that is usually reserved for severe infections. Acute eosinophilic pneumonia (AEP) is an increasingly rare side effect that can manifest after its use. Our patient is a 79-year-old male who was admitted for a left total knee arthroplasty infection. After daptomycin was started, he developed AEP. The offending agent was stopped, the appropriate medical treatment was given, and his symptoms significantly improved. This case illustrates an uncommon side effect of daptomycin. Prompt medical recognition is paramount for medication discontinuation and adequate medical care.

Keywords: chronic kidney disease (ckd); daptomycin; daptomycin induced pneumonitis; daptomycin-induced acute eosinophilic pneumonia; septic arthritis.

Publication types

  • Case Reports