Follow-up CT of "reversed halo sign" in SARS-CoV-2 delta VOC pneumonia: A report of two cases

J Med Virol. 2022 Apr;94(4):1289-1291. doi: 10.1002/jmv.27533. Epub 2021 Dec 29.

Abstract

In December 2019, a new type of virus, coronavirus disease 2019 broke out globally and caused great harm. The virus mutates rapidly, and more research reports are urgently needed to increase our understanding of the disease. We found the reversed halo sign (RHS) occurred in the imaging manifestations of severe acute respiratory syndrome coronavirus 2 delta variant of concern pneumonia. In the absence of pathology, the mechanism is unknown. Therefore, we reported two cases of RHS and tried to speculate the pathological mechanism through multiple computed tomography follow-up comparisons to judge the prognosis of the disease.

Keywords: SARS coronavirus; coronavirus; imaging techniques; research and analysis methods; virus classification.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • COVID-19 / diagnostic imaging*
  • COVID-19 / pathology
  • COVID-19 / virology
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Pneumonia / diagnostic imaging
  • Pneumonia / pathology
  • Pneumonia / virology
  • Prognosis
  • SARS-CoV-2 / isolation & purification
  • SARS-CoV-2 / pathogenicity*
  • Tomography, X-Ray Computed

Supplementary concepts

  • SARS-CoV-2 variants