Genetic analysis of a SARS-CoV-2 Omicron variant from a Chinese traveller returning from overseas

Emerg Microbes Infect. 2022 Dec;11(1):306-309. doi: 10.1080/22221751.2022.2025747.

Abstract

Since the SARS-CoV-2 Omicron variant was first reported from South Africa, it has rapidly spread in over 100 countries. Only two cases infected by the Omicron variant were recently identified in China. The one case in Guangzhou has a relatively long incubation time and mild symptoms. Analysis of the complete viral genome sequence shows three missing Omicron unique mutations and one additional mutation in the newly characterized genome. These unique mutations may be related to the clinical presentation in this case.

Keywords: COVID-19; Omicron variant; SARS-CoV-2; infection; mutation.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • COVID-19*
  • China
  • Humans
  • SARS-CoV-2*
  • South Africa

Supplementary concepts

  • SARS-CoV-2 variants

Grants and funding

This work was supported by National Key Research and Development Program of China (2021YFC2301500), Science and Technology Planning Project of Guangzhou (202102100001), The Key Project of Medicine Discipline of Guangzhou (2021-2023-11), National Natural Science Foundation of China (81773758 and 31670162).