Pulmonary thromboembolism and alveolar hemorrhage as initial manifestations of systemic lupus erythematosus

Lupus. 2022 Jan;31(1):116-124. doi: 10.1177/09612033211066481. Epub 2022 Jan 18.

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease that affects multiple organs. SLE can affect the lung, the pulmonary vasculature, and the pleura. A 38-year-old female with limb pain and ecchymosis who later developed pulmonary thromboembolism and alveolar hemorrhage is presented here. Clinical, imaging, laboratory, and histopathological evidence is presented. The patient met the European League Against Rheumatism (EULAR) and the American College of Rheumatology (ACR) criteria for SLE. Furthermore, the patient had a Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) score of 35; thus, indicating severe disease. This case is an example of concomitant venous and arterial lung complications in an SLE patient.

Keywords: alveolar hemorrhage; pulmonary thromboembolism; systemic lupus erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Hemorrhage / etiology
  • Humans
  • Lupus Erythematosus, Systemic* / complications
  • Pulmonary Embolism* / diagnostic imaging
  • Pulmonary Embolism* / etiology
  • Rheumatic Diseases*
  • Rheumatology*
  • United States