Evaluation of fidaxomicin use in community hospitals after a clinical guideline change at a large health system and opportunities for stewardship

Infect Control Hosp Epidemiol. 2023 Feb;44(2):312-314. doi: 10.1017/ice.2021.456. Epub 2022 Jan 24.

Abstract

After updating our health system's Clostridioides difficile treatment protocols in 2018, we reviewed 104 unique hospital encounters involving fidaxomicin at 10 community hospitals. Half (50%) of regimens were adherent to our guidelines, with infectious diseases (ID) providers were frequently nonadherent. Antimicrobial stewardship programs are important for facilitating best practices, even among ID specialists.

Keywords: antimicrobial stewardship; fidaxomicin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antimicrobial Stewardship*
  • Clostridioides
  • Clostridioides difficile*
  • Clostridium Infections* / drug therapy
  • Fidaxomicin / therapeutic use
  • Hospitals, Community
  • Humans

Substances

  • Anti-Bacterial Agents
  • Fidaxomicin