Lamar Dodd was a 20th century American artist, the long-term director of the Lamar Dodd School of Art at the University of Georgia, and an arts advocate raised in LaGrange, Georgia. In the late 1970s after serving as a cultural emissary to the U.S. Department of State and as an artist for the National Aeronautics and Space Administration (NASA), Dodd explored the complexities and mysteries of cardiac surgery. The result of this artistic inquiry was The Heart Series, a profound collection of more than 50 works of art that explore the medical sciences and cardiothoracic surgery. This article reviews Dodd's artistic career and explores the ability of the visual arts to communicate scientific content and capture the transcendent elements of medical intervention. Special attention is paid to the unique relationship Dodd shared with his hometown community in LaGrange, the Wellstar West Georgia Medical Center, Robert Copeland (founder and long-term director of the Copeland Heart and Vascular Center at the Wellstar West Georgia Medical Center), and local philanthropist, Fuller E. Callaway, Jr.