Management of Cardiac Symptoms in Amyloidosis

Phillip King; Andrew M Kates

doi:10.1016/j.amjmed.2022.02.005

Management of Cardiac Symptoms in Amyloidosis

Am J Med. 2022 Apr:135 Suppl 1:S9-S12. doi: 10.1016/j.amjmed.2022.02.005. Epub 2022 Feb 27.

Authors

Phillip King¹, Andrew M Kates²

Affiliations

¹ Cardiovascular Division, Washington University School of Medicine, St. Louis, Mo.
² Cardiovascular Division, Washington University School of Medicine, St. Louis, Mo. Electronic address: akates@wustl.edu.

PMID: 35235819
DOI: 10.1016/j.amjmed.2022.02.005

Abstract

Cardiac amyloidosis (CA) results in symptoms of heart failure, atrial and ventricular arrhythmias, conduction disturbances, and profound autonomic dysfunction. These symptoms present unique management challenges as compared with patients without CA, and can be very debilitating. Thus, management of the cardiovascular symptoms of these patients plays a central role in their care. This review presents an overview of the typical cardiovascular manifestations encountered in patients with CA and highlights the key management considerations for each.

Keywords: Aortic stenosis; Atrial fibrillation; Cardiac amyloidosis; Conduction disease; Device therapy; Heart failure; Orthostatic hypotension; Symptom management; Ventricular arrhythmias.

Publication types

Review

MeSH terms

Amyloidosis* / complications
Amyloidosis* / diagnosis
Amyloidosis* / therapy
Arrhythmias, Cardiac / etiology
Arrhythmias, Cardiac / therapy
Heart Atria
Heart Diseases* / diagnosis
Heart Diseases* / etiology
Heart Diseases* / therapy
Heart Failure* / etiology
Heart Failure* / therapy
Humans