A rare presentation of blastomycosis as a multi-focal infection involving the spine, pleura, lungs, and psoas muscles in a Saudi male patient: a case report

BMC Infect Dis. 2022 Mar 7;22(1):228. doi: 10.1186/s12879-022-07203-x.

Abstract

Background: Blastomycosis is a disease caused by the fungus Blastomyces-a thermally dimorphic fungus that can cause granulomatous and/or purulent infection.

Case presentation: We report here a case of chronic blastomycosis infection in a 24-year-old male patient from Saudi Arabia who presented with recurrent skin abscesses associated with deep-seated and multilevel paraspinal (dorsal and lumbar) collections and bilateral empyema with pulmonary involvement and bilateral psoas abscesses. The diagnosis was made after a CT-guided pleural biopsy revealed the characteristic histopathological findings of blastomycosis. The patient underwent several drainage procedures and was successfully treated with a long-term course of oral itraconazole.

Conclusions: Chronic blastomycosis may have clinical and radiologic features similar to thoracic tuberculosis or malignant disease. There is no definite clinical symptom of blastomycosis, and thus a high degree of suspicion is required for early diagnosis. This case is a rare form of blastomycosis with chronic multifocal purulent infection and is the second case of blastomycosis reported in Saudi Arabia.

Keywords: Blastomycosis; Pleural effusion; Psoas muscles; Pulmonary nodules.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Blastomycosis* / diagnosis
  • Blastomycosis* / drug therapy
  • Focal Infection* / drug therapy
  • Humans
  • Lung / pathology
  • Male
  • Pleura / pathology
  • Psoas Muscles / pathology
  • Saudi Arabia
  • Young Adult

Substances

  • Antifungal Agents