Massive ascites due to lupus peritonitis in a patient with pre-eclampsia and systemic lupus erythematosus: a case report

BMC Pregnancy Childbirth. 2022 Mar 14;22(1):203. doi: 10.1186/s12884-022-04550-0.

Abstract

Background: Patients with systemic lupus erythematosus (SLE) are associated with pre-eclampsia. Pre-eclampsia can have systemic manifestations, such as ascites. Lupus peritonitis, a rare condition in patients with SLE, can also cause ascites.

Case presentation: A 31-year-old woman, primigravida, with SLE had a blood pressure of 170/110 mmHg and proteinuria at 29 weeks of gestation. She was diagnosed with pre-eclampsia. Her blood pressure was stabilized by an antihypertensive drug. At 30 weeks of gestation, a cesarean section was performed for maternal safety because of decreased urine output and massive ascites. Postoperatively, re-accumulation of ascites was observed. On the fourth postoperative day, ascites (approximately 3 L) was discharged from the cesarean section wound. A decrease in serum complement concentrations was observed, and she was diagnosed as having lupus peritonitis. The steroid dose was increased and she recovered well thereafter.

Conclusions: Ascites occurs in pre-eclampsia and SLE, but determining which of these conditions causes ascites can be difficult. However, careful observation is necessary because of the differences in treatment of these two conditions.

Keywords: Ascites; Peritonitis; Pre-eclampsia; Systemic lupus erythematosus.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Ascites / etiology*
  • Cesarean Section
  • Female
  • Humans
  • Immunotherapy
  • Lupus Erythematosus, Systemic / complications*
  • Peritonitis / complications*
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy
  • Pre-Eclampsia / diagnosis*
  • Pregnancy
  • Pregnancy Complications*
  • Pregnancy Outcome
  • Treatment Outcome