Atypical Hemolytic Uremic Syndrome in a Patient With Metastatic Peritoneal Serous Carcinoma: A Case Report

Cureus. 2022 Feb 26;14(2):e22624. doi: 10.7759/cureus.22624. eCollection 2022 Feb.

Abstract

Atypical hemolytic uremic syndrome (HUS) is a part of a large category of diseases known as thrombotic microangiopathies that present with hemolytic anemia, thrombocytopenia, and target organ damage mostly characterized by acute kidney injury. It is a rare and challenging diagnosis due to the complex pathophysiology underlying the disease and its overlap with other conditions. We report the case of atypical hemolytic uremic syndrome in a 61-year-old female with a history of metastatic peritoneal serous carcinoma of the ovary presenting with anemia and acute renal failure.

Keywords: atypical hemolytic syndrome; eculizumab; kidney failure; microangiopathic hemolytic anemia; peritoneal serous carcinoma; thrombotic microangiopathy.

Publication types

  • Case Reports