Impact of covid-19 on long-term oxygen therapy 2020: A nationwide study in Sweden

PLoS One. 2022 Apr 8;17(4):e0266367. doi: 10.1371/journal.pone.0266367. eCollection 2022.

Abstract

Introduction: Covid-19 can cause chronic hypoxic respiratory failure, but the impact on the need for long-term oxygen therapy (LTOT) is unknown. The aim was to investigate change in incidence and characteristics of patients starting LTOT in Sweden 2020 after the outbreak of the pandemic.

Material and methods: Population-based observational study using data from the National Registry for Respiratory Failure (Swedevox) and from a survey to all centres prescribing LTOT in Sweden. Swedevox data provided information on incidence of LTOT and characteristics of patients starting LTOT during 2015-2020.

Results: Between March-Dec 2020, 131 patients started LTOT due to covid-19, corresponding to 20.5% of incident LTOT in Sweden. Compared with 2015-19, the total number of patients starting LTOT did not increase. No significant differences in patient characteristics or underlying causes of hypoxemia were found between patients starting LTOT during 2020 compared 2015-2019. The majority of the LTOT centres estimated that, since the start of the pandemic, the incidence of LTOT was unchanged and the time devoted for LTOT work was the same or slightly less.

Conclusions: Covid-19 caused one fifth of all LTOT starts during the pandemic in 2020. The LTOT incidence overall did not increase possibly due to reduction in other infections.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19* / epidemiology
  • COVID-19* / therapy
  • Humans
  • Hypoxia / epidemiology
  • Hypoxia / etiology
  • Hypoxia / therapy
  • Oxygen
  • Oxygen Inhalation Therapy / adverse effects
  • Pulmonary Disease, Chronic Obstructive* / therapy
  • Respiratory Insufficiency* / therapy
  • Sweden / epidemiology
  • Time Factors

Substances

  • Oxygen

Grants and funding

Magnus Ekström was supported by unrestricted grants from the Swedish Society for Medical Research and the Swedish Research Council (Dnr 2019-02081). There was no additional external funding received for this study.